Prolotherapy treatments are usually administered every 1-4 weeks and vary depending on the individual. The average number of treatments needed is 4-6, but the number of treatments can vary from 2-10, depending on persistence of symptoms. The reported success rate for prolotherapy has been as high as 95%.
Side effects include pain and bruising in the injected area, allergic reaction to the solution, headaches and (rarely) nerve damage.
Although prolotherapy has been around for decades, most insurances consider it an investigational treatment and therefore do not cover it. The typical cost of prolotherapy is $150-$400 depending on the area treated.